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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease multiple endocrine neoplasia type 1
Comorbidity C1140680|ovarian ca
Sentences 9
PubMedID- 26183052 The cases were all women in denmark with epithelial ovarian cancer diagnosed during 2000-2009 (paper 1) and 2000-2011 (papers 2 and 3), identified in the cancer registry.
PubMedID- 23063762 The "leuven" paclitaxel/carboplatin weekly regimen in patients with recurrent ovarian cancer, a retrospective study.
PubMedID- 20385032 Computed tomographic (ct) scans of the abdomen in a patient with advanced ovarian cancer and brca mutation family history showed a reduction in the size of a peritoneal tumor nodule by 66% over a 4-month treatment period during which she received a potent parp1 inhibitor, olaparib, at a dose of 100 mg, twice daily, for 2 of every 3 weeks.
PubMedID- 21742586 Treatment was discontinued prior to 6 cycles in 2 of 12 patients secondary to progression in one case and to grade 4 neutropenia and thrombocytopenia in another.the combination of intravenous gemcitabine and an intraperitoneal platinum agent appears to be a feasible regimen in patients with ovarian cancer.
PubMedID- 22396450 ovarian cancer in women is a complex and deadly disease, where the molecular events that initiate and control tumor formation remain poorly defined.
PubMedID- 20576343 The purpose of this study was to provide preliminary toxicity data of carboplatin-based ip chemotherapy and to evaluate the feasibility of this chemotherapy regimen in patients with ovarian cancer after primary debulking surgery.
PubMedID- 25834466 ovarian cancer affected 83% of women in c2007-01.
PubMedID- 25599660 As for the single irinotecan regimen in patients with platinum-resistant ovarian cancer, a phase ii study demonstrated that irinotecan of 300 mg/m2/3 weeks had an orr of 17.2 % and a median pfs of 2.8 months [30].
PubMedID- 21792011 Possible use of ca-125 level normalization after the third chemotherapy cycle in deciding on chemotherapy regimen in patients with epithelial ovarian cancer: brief report.

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